Background The use of lengthy, detailed, and complex informed consent forms is of paramount concern in biomedical research as it may not truly promote the rights and interests of research participants. The extent of information in ICFs has been the subject of debates for decades; however, no clear guidance is given. Thus, the objective of this study was to determine the perspectives of research participants about the type and extent of information they need when they are invited to participate in (...) biomedical research. Methods This multi-center, cross-sectional, descriptive survey was conducted at 54 study sites in seven Asia-Pacific countries. A modified Likert-scale questionnaire was used to determine the importance of each element in the ICF among research participants of a biomedical study, with an anchored rating scale from 1 to 5. Results Of the 2484 questionnaires distributed, 2113 were returned. The majority of respondents considered most elements required in the ICF to be ‘moderately important’ to ‘very important’ for their decision making. Major foreseeable risk, direct benefit, and common adverse effects of the intervention were considered to be of most concerned elements in the ICF. Conclusions Research participants would like to be informed of the ICF elements required by ethical guidelines and regulations; however, the importance of each element varied, e.g., risk and benefit associated with research participants were considered to be more important than the general nature or technical details of research. Using a participant-oriented approach by providing more details of the participant-interested elements while avoiding unnecessarily lengthy details of other less important elements would enhance the quality of the ICF. (shrink)

The notion that our society, its education system and its intellectual life, is characterised by a split between two cultures – the arts or humanities on one hand and the sciences on the other – has a long history. But it was C. P. Snow's Rede lecture of 1959 that brought it to prominence and began a public debate that is still raging in the media today. This fiftieth anniversary printing of The Two Cultures and its successor piece, A Second (...) Look features an introduction by Stefan Collini, charting the history and context of the debate, its implications and its afterlife. The importance of science and technology in policy run largely by non-scientists, the future for education and research, and the problem of fragmentation threatening hopes for a common culture are just some of the subjects discussed. (shrink)

The notion that our society, its education system and its intellectual life, is characterised by a split between two cultures – the arts or humanities on one hand, and the sciences on the other – has a long history. But it was C. P. Snow's Rede lecture of 1959 that brought it to prominence and began a public debate that is still raging in the media today. This 50th anniversary printing of The Two Cultures and its successor piece, A Second (...) Look features an introduction by Stefan Collini, charting the history and context of the debate, its implications and its afterlife. The importance of science and technology in policy run largely by non-scientists, the future for education and research, and the problem of fragmentation threatening hopes for a common culture are just some of the subjects discussed. (shrink)

Dan Baras has recently argued for the claim that Theistic Mathematical Platonism fares no better than Mathematical Platonism with respect to explaining why our mathematical beliefs are correlated with mind-independent mathematical truths. In this paper I argue that, insofar as TMP provides a proximate or local explanation for this truth-tracking correlation whereas MP fails to offer any corresponding explanation, Baras’s claim that TMP fares no better than MP with respect to explaining this correlation is false.

Offering an original perspective on the central project of Descartes' Meditations, this book argues that Descartes' free will theodicy is crucial to his refutation of skepticism. A common thread runs through Descartes' radical First Meditation doubts, his Fourth Meditation discussion of error, and his pious reconciliation of providence and freedom: each involves a clash of perspectives-thinking of God seems to force conclusions diametrically opposed to those we reach when thinking only of ourselves. Descartes fears that a skeptic could exploit this (...) clash of perspectives to argue that Reason is not trustworthy because self-contradictory. To refute the skeptic and vindicate the consistency of Reason, it is not enough for Descartes to demonstrate that our Creator is perfect; he must also show that our errors cannot prove God's imperfection. To do this, Descartes invokes the idea that we err freely. However, prospects initially seem dim for this free will theodicy, because Descartes appears to lack any consistent or coherent understanding of human freedom. In an extremely in-depth analysis spanning four chapters, Ragland argues that despite initial appearances, Descartes consistently offered a coherent understanding of human freedom: for Descartes, freedom is most fundamentally the ability to do the right thing. Since we often do wrong, actual humans must therefore be able to do otherwise-our actions cannot be causally determined by God or our psychology. But freedom is in principle compatible with determinism: while leaving us free, God could have determined us to always do the good. Though this conception of freedom is both consistent and suitable to Descartes' purposes, when he attempts to reconcile it with divine providence, Descartes's strategy fails, running afoul of his infamous doctrine that God created the eternal truths. (shrink)

: The principle of alternative possibilities (PAP) says that doing something freely implies being able to do otherwise. I show that Descartes consistently believed not only in PAP, but also in clear and distinct determinism (CDD), which claims that we sometimes cannot but judge true what we clearly perceive. Because Descartes thinks judgment is always a free act, PAP and CDD seem contradictory, but Descartes consistently resolved this apparent contradiction by distinguishing between two senses of 'could have done otherwise.' In (...) one sense alternative possibilities are necessary for freedom and in another they are not. I discuss three possible interpretations of the two senses. (shrink)

We offer a novel interpretation of the argumentative role that Meditation IV plays within the whole of the Meditations. This new interpretation clarifies several otherwise head-scratching claims that Descartes makes about Meditation IV, and it fully exonerates the Fourth Meditation from either raising or exacerbating Descartes’ circularity problems.

C P Ormell; Ideology and the Reform of School Mathematics, Journal of Philosophy of Education, Volume 3, Issue 1, 30 May 2006, Pages 37–54, https://doi.org/10.1.

The principle of alternative possibilities (PAP) says that doing something freely implies being able to do otherwise. I show that Descartes consistently believed not only in PAP, but also in clear and distinct determinism (CDD), which claims that we sometimes cannot but judge true what we clearly perceive. Because Descartes thinks judgment is always a free act, PAP and CDD seem contradictory, but Descartes consistently resolved this apparent contradiction by distinguishing between two senses of 'could have done otherwise.' In one (...) sense alternative possibilities are necessary for freedom and in another they are not. I discuss three possible interpretations of the two senses. (shrink)

Speeches delivered in Tamil at various schools in Tamil Nadu, during 2010-2015, by A.P.J. Abdul Kalam, 1931-2015, former President of India.

In an influential article, Anthony Kenny charged that (a) the view of freedom in Descartes’ “1645 letter to Mesland” is incoherent, and (b) that this incoherence was present in Descartes’ thought from the beginning. Against (b), I argue that such incoherence would rather support Gilson’s suspicions that the 1645 letter is dishonest. Against (a), I offer a close reading of the letter, showing that Kenny’s objection seems plausible only if we misconstrue a key ambiguity in the text. I close by (...) defending Descartes against some related worries of my own about the degrees of Cartesian freedom. I conclude that there is really no good reason to deny that Descartes’ view in the 1645 letter is both internally coherent and a genuine explication of the Meditations’ account of freedom. (shrink)

God’s providence appears to threaten the existence of human freedom. This paper examines why Descartes considered this threat merelyapparent. Section one argues that Descartes did not reconcile providence and freedom by adopting a compatibilist conception of freedom. Sections two and three argue that for Descartes, God’s superior knowledge allows God to providentially arrange free choices without causally determining them. Descartes’ position thus strongly resembles the “middle knowledge” solution of the Jesuits. Section four examines the problematic relationship between this solution and (...) the creation of the eternal truths, arguing that Descartes’ position depends on his unique understanding of divine simplicity. (shrink)

We formalise the notion of those infinite binary sequences z that admit a single program P which expresses the entire algorithmical structure of z. Such a program P minimizes the information which must be used in a relative computation for z. We propose two concepts with different strength for this notion, the learnable and the super-learnable sequences. We establish three different equivalent characterizations of learnable (super-learnable, resp.) sequences. In particular, we prove that a sequences z is learnable (super-learnable, resp.) if (...) and only if there is a computable probability measure p such that p is Schnorr (Martin-Lof, resp.) p-random. There is a recursively enumerable sequence which is not learnable. The learnable sequences are invariant with respect to all total and effective transformations of infinite binary sequences. (shrink)

The research investigates the role of leadership in the transformation of denominational structures towards a missional ecclesiology, and focusses on the Highveld Synod of the Dutch Reformed Church. It describes the missional journey of the denomination, and interprets the transformation. The theory of ‘complex leadership’ in complex systems is applied to the investigation of the impact of leadership on a denominational structure. The theory identifies three mechanisms used by leaders as enablers in emergent, self-organisation systems: Leaders disrupt existing patterns, they (...) encourage novelty, and they act as sensemakers. These insights are applied as a tool to interpret the missional transformation of a denomination. (shrink)

In the Fourth Meditation, Descartes asks: 'If God is no deceiver, why do we sometimes err?' Descartes's answer (despite initial appearances) is both systematic and necessary for his epistemological project. Two atheistic arguments from error purport to show that reason both proves and disproves God's existence. Descartes must block them to escape scepticism. He offers a mixed theodicy: the value of free will justifies God in allowing our actual errors, and the perfection of the universe may justify God in making (...) us able to err. Though internally coherent, Descartes's theodicy conflicts with his view of divine providence. (shrink)

Herodotus has often been considered the Father of Ethnography no less than the Father of History. It comes as a paradox, then, that he has been taxed with confusion in his use of two terms that recur over and over in his discussion of peoples, ἕθνος and γνος. Here is the formulation of Raymond Weil:Hérodote definit mal l‘ethnos’. C'est pour lui tantôot une subdivision du ‘génos’, tantôt au contraire un ensemble de ‘géné’. Ainsi 1' ‘ethnos’ des Médes, comme celui des (...) Scythes, groupe plusieurs γνεα. Mais cet ‘ethnos’ scythe porte aussi le nom de ‘génos’, et comprend des ἕθνεα. Les Athéniens sont un ‘ethnos’ hellénique qui fait partie du ‘génos’ ionien, les Lacédémoniens un ‘ethnos’ pélasgique à rattacher au ‘génos’ dorien. (shrink)

Herodotus has often been considered the Father of Ethnography no less than the Father of History. It comes as a paradox, then, that he has been taxed with confusion in his use of two terms that recur over and over in his discussion of peoples, θνος and γνος. Here is the formulation of Raymond Weil: Hérodote definit mal l‘ethnos’. C'est pour lui tantôot une subdivision du ‘génos’, tantôt au contraire un ensemble de ‘géné’. Ainsi 1' ‘ethnos’ des Médes, comme celui (...) des Scythes, groupe plusieurs γνεα. Mais cet ‘ethnos’ scythe porte aussi le nom de ‘génos’, et comprend des θνεα. Les Athéniens sont un ‘ethnos’ hellénique qui fait partie du ‘génos’ ionien, les Lacédémoniens un ‘ethnos’ pélasgique à rattacher au ‘génos’ dorien. (shrink)

Background: Funding organisations and research ethics committees should play a part in strengthening attention to gender equality in clinical research. In the research policy of European Union , funding measures have been taken to realise this, but such measures are lacking in the EU policy regarding RECs.Objective: To explore how RECs in Austria, Germany, Ireland, The Netherlands and Sweden deal with gender equality issues by asking two questions: Do existing procedures promote representation of women and gender expertise in the committee? (...) How are sex and gender issues dealt with in protocol evaluation?Methods: Two RECs were selected from each country. Data were obtained through interviews with key informants and content analysis of relevant documents .Results: All countries have rules to ensure the presence of women on RECs; gender expertise is not required. Drug study protocols are carefully evaluated, sometimes on a formal basis, as regards the inclusion of women of childbearing age. The reason for excluding either one of the sexes or including specific groups of women or making a gender-specific risk–benefit analysis are investigated by some RECs. Such measures are, however, neither defined in the regulations nor integrated in review tools.Conclusions: The RECs investigated in five European member states are found to pay limited attention to gender equality in their working methods and, in particular in protocol evaluation. Policy and regulations of EU are needed to strengthen attention to gender equality in the work of RECs. (shrink)

Between 1069, the year of his arrival at St. Martin in Mainz, where he spent the rest of his life in voluntary enclosure in a cell, and his death in 1082, the Irish monk Marianus Scottus dedicated countless hours to assembling the most sophisticated and comprehensive work on historical chronology that had ever been produced by a Latin writer up to that time. The fruits of his labors became a massive world chronicle, completed in 1076, whose most famous innovation consisted (...) in a far-reaching correction to the Christian, or “common,” era, which had been introduced by Dionysius Exiguus in the sixth century. Having compared the data of the Easter computus with the chronological parameters traditionally associated with the passion of Christ—the fifteenth day of the moon on Friday, 25 March—Marianus found that the only year in which the numbers could be made to fit was AD 12 rather than the traditionally accepted AD 34. As a result, he decided to predate the life of Jesus by twenty-two years, assigning his birth to the year corresponding to 22 BC. This gave rise to a new “corrected” era , which he used alongside its Dionysiac equivalent. (shrink)

This paper suggests that moral neutrality erodes the liberal practices which sustain a free society. It supports the Polanyian claim that a free society is the political arrangement which is best able to realise universal ideals.

Reprint. Originally published: Rajini's punchtantra: value statements on business and life management. Chennai: New Horizon Media, 2010.